Augmentation of murine tumor necrosis factor production by amphotericin B in vitro and in vivo.
作者信息
Tokuda Y, Tsuji M, Yamazaki M, Kimura S, Abe S, Yamaguchi H
机构信息
Department of Microbiology and Immunology, School of Medicine, Teikyo University, Tokyo, Japan.
出版信息
Antimicrob Agents Chemother. 1993 Oct;37(10):2228-30. doi: 10.1128/AAC.37.10.2228.
Abstract
Murine peritoneal macrophages were preincubated with amphotericin B (AMPH) and were then stimulated with bacterial lipopolysaccharide or streptococcal preparation (OK432). These macrophages produced a large amount of tumor necrosis factor. When administered to mice, the priming activity of amphotericin B for tumor necrosis factor production in vivo was also observed.
摘要
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