Hof H
MMW Munch Med Wochenschr. 1976 Nov 12;118(46):1485-8.
Severe vitamin A deficiency undoubtedly leads to increased susceptibility to infection. On the one hand this is due to the mucosae being damaged by the vitamin deficiency to the extent that these natural barriers are more easily overcome by pathogens. On the other hand, however, also the general defensive condition is weakened, which is partly attributable to a decrease in lymphatic tissue. An increased supply of vitamin A may possibly intensify the production of antibodies, but a definitely positive effect on the course of infections is not established. Therefore, the characterization of vitamin A as "anti-infective" is justified to some extent only.
严重的维生素A缺乏无疑会导致易感性增加。一方面，这是由于维生素缺乏对黏膜造成损害，以至于这些天然屏障更容易被病原体突破。然而，另一方面，整体防御状态也会减弱，部分原因是淋巴组织减少。增加维生素A的供应可能会增强抗体的产生，但对感染病程的明确积极作用尚未得到证实。因此，将维生素A称为“抗感染”在一定程度上只是合理的。
