Simpson J M, Silveri C P, Balderston R A, Simeone F A, An H S
Department of Orthopaedic Surgery, Rothman Institute, Pennsylvania Hospital, Philadelphia 19107.
J Bone Joint Surg Am. 1993 Dec;75(12):1823-9. doi: 10.2106/00004623-199312000-00013.
The results for sixty-two patients who had had a diagnosis of diabetes mellitus and lumbar disc disease or spinal stenosis and had been managed with a posterior decompressive procedure were compared, in a retrospective study, with those for sixty-two age and sex-matched non-diabetic (control) patients who had had similar operative procedures. Forty-four of the sixty-two diabetic patients and fifty-five of the non-diabetic patients were available for long-term follow-up (mean, five and seven years, respectively). Among the diabetic patients, there were high rates of postoperative infection and prolonged hospitalization compared with the rates for the control group. The long-term result was excellent or good for seventeen (39 per cent) of the forty-four patients who had diabetes mellitus and for fifty-two (95 per cent) of the fifty-five non-diabetic patients. The poor results in the diabetic patients may have been related to coexisting diabetic neuropathy, to the associated microvascular disease that affects the spinal nerve roots in diabetic patients, or to the failure of the nerve roots of these patients to recover after decompressive procedures.
在一项回顾性研究中，将62例被诊断患有糖尿病且患有腰椎间盘疾病或椎管狭窄并接受了后路减压手术的患者的结果，与62例年龄和性别匹配的、接受了类似手术的非糖尿病（对照）患者的结果进行了比较。62例糖尿病患者中有44例，非糖尿病患者中有55例可进行长期随访（平均分别为5年和7年）。与对照组相比，糖尿病患者术后感染率和住院时间延长率较高。44例糖尿病患者中有17例（39%）的长期结果为优或良，55例非糖尿病患者中有52例（95%）的长期结果为优或良。糖尿病患者的不良结果可能与并存的糖尿病神经病变、影响糖尿病患者脊神经根的相关微血管疾病有关，或者与这些患者的神经根在减压手术后未能恢复有关。
