Butkevich I P, Kassil' V G
Zh Evol Biokhim Fiziol. 1993 May-Jun;29(3):280-9.
Effects of stimulation of areas of the negative reinforcement in hypothalamus and adjacent sites on the nociceptive evoked potentials (EP), recorded in the thalamic parafascicular complex to electrical skin stimulation of the hind paw in 30-40 days old rabbits were investigated. The stimulation of areas of the negative reinforcement in the anaesthetized animals resulted in the inhibition of the EP. Points, yielding the active-defense behaviour in the behavioural experiments, inhibited the EPs in the electrophysiological tests at the smaller current level (50-80%), than points, yielding the passive-defense behaviour (80-110%). On the contrary, the recovery period of the EP's parameters after the ceasing of the stimulation was shorter, if points were connected with the active-defense but not the passive-defense behaviour. The data obtained are considered in comparison with previous findings obtained in the investigation on the rabbits of the same age under the stimulation of areas of the positive reinforcement.
研究了刺激30 - 40日龄家兔下丘脑及邻近部位的负强化区域对丘脑束旁复合体记录的伤害性诱发电位（EP）的影响，该诱发电位是通过对后爪进行皮肤电刺激而记录的。对麻醉动物的负强化区域进行刺激会导致EP受到抑制。在行为实验中引发主动防御行为的部位，在电生理测试中，与引发被动防御行为的部位相比，在较小电流水平（50 - 80%）时就能抑制EP。相反，如果这些部位与主动防御行为而非被动防御行为相关，那么刺激停止后EP参数的恢复期会更短。将获得的数据与之前在相同年龄家兔的正强化区域刺激研究中得到的结果进行了比较。
