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[家兔生命早期丘脑皮质诱发电位的年龄相关动态变化]

[Age-related dynamics of thalamic-cortical evoked potentials in the rabbit in the early period of life].

作者信息

Shimko I A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Sep-Oct;37(5):946-53.

PMID:3433938
Abstract

Data have been obtained on development of evoked potentials in the sensorimotor cortex to electrical stimulation of the thalamic ventroposterolateral nucleus (VPL) in rabbits in early ontogeny. In 3-5 days rabbits, under four times increase of threshold electric stimulation of VPL the thalamocortical response (TCR) is presented by a positive-negative potential with a long latency and minimum amplitude parameters. Second and third TCR positive components to increasing of threshold value of electric stimulation 4 times, are differentiated from 7-8 days age. Age dynamics of TCR amplitude-temporal parameters is characterized by a shortening of latency and an increase of oscillations amplitude, most expressed at 2-3 weeks of postnatal life. TCR of one month rabbit to increased threshold electrical stimulation of VPL is presented by short-latency positive-negative oscillation with a positive phase consisting of three components with successively increasing amplitudes.

摘要

已获得关于家兔个体发育早期,感觉运动皮层对丘脑腹后外侧核(VPL)电刺激诱发电位的发育数据。在3至5日龄的家兔中,当VPL的阈下电刺激增加四倍时,丘脑皮质反应(TCR)表现为具有长潜伏期和最小幅度参数的正负电位。随着电刺激阈值增加四倍,TCR的第二和第三正向成分在7至8日龄时开始分化。TCR幅度-时间参数的年龄动态特征是潜伏期缩短和振荡幅度增加,在出生后2至3周时最为明显。1月龄家兔对VPL阈上电刺激的TCR表现为短潜伏期正负振荡,正相由三个幅度依次增加的成分组成。

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引用本文的文献

1
Layer-by-layer analysis of the components of thalamocortical responses of the sensorimotor cortex in the rabbit during ontogenesis.家兔个体发育过程中感觉运动皮层丘脑皮层反应成分的逐层分析。
Neurosci Behav Physiol. 1992 Jul-Aug;22(4):268-74. doi: 10.1007/BF01182864.