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[标记RNA从巨噬细胞向淋巴细胞转移的自身对照研究(作者译)]

[Autographical investigations of the transfer of labeled RNA from macrophages to lymphocytes (author's transl)].

作者信息

Jonas L, Dörfling P, Barten M, Tessmann D

出版信息

Acta Histochem. 1976;56(2):301-8.

PMID:826098
Abstract

By means of electron microscopic autoradiography we demonstrated a radioactivity in mice spleen lymphocytes after a common cultivation for 1 h with 3H-uridine marked autologian macrophages, washed profoundly. The radioactivity in lymphocytes is small after contact with unstimulated macrophages and is markedly increased after common cultivation with antigen stimulated macrophages. A transfer of RNA molecules of macrophages into lymphocytes is supposed.

摘要

通过电子显微镜放射自显影术,我们发现,在与经深度洗涤的用³H-尿苷标记的自体巨噬细胞共同培养1小时后,小鼠脾脏淋巴细胞中存在放射性。与未受刺激的巨噬细胞接触后,淋巴细胞中的放射性较低,而与抗原刺激的巨噬细胞共同培养后,放射性显著增加。推测存在巨噬细胞的RNA分子向淋巴细胞的转移。

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