Vinatier D, Lefebvre-Maunoury C, Bernardi C
Maternité de Pavillon Victor-Olivier, Service de Gynécologie et d'Obstétrique, CHRU Lille.
J Gynecol Obstet Biol Reprod (Paris). 1993;22(6):581-91.
Sevellar cellular types are involved together in the cyclical functioning of the ovary. Regulating this co-operation between cells are intercellular systems of communication both autocrine and paracrine. The immune system that is present in the ovary seems to have an important role among the regulatory factors. Cytokines are the vectors of intercellular communication. The authors after studying the recent literature show how the immune system elements undergo cyclical variations corresponding to the ovulatory cycle. Reciprocal co-operation between the different cells is brought in to play at all stages of growth and of atrophy of the follicle. The knowledge of these networks for regulation make it possible to understand what is going on better and to work out a more appropriate treatment for certain pathologies such as premature menopause and unforeseen responses to certain forms of stimulation of ovulation.
多种细胞类型共同参与卵巢的周期性功能。调节细胞间这种合作的是自分泌和旁分泌的细胞间通讯系统。卵巢中存在的免疫系统似乎在调节因子中发挥着重要作用。细胞因子是细胞间通讯的载体。作者在研究了近期文献后,展示了免疫系统元件如何经历与排卵周期相对应的周期性变化。不同细胞之间的相互合作在卵泡生长和萎缩的所有阶段都发挥作用。对这些调节网络的了解有助于更好地理解正在发生的事情,并为某些病症(如过早绝经和对某些排卵刺激形式的意外反应)制定更合适的治疗方案。