Mayatepek E, Seebass E, Hingst V, Kroeger A, Sonntag H G
University Children's Hospital, Heidelberg, Germany.
J Diarrhoeal Dis Res. 1993 Sep;11(3):169-71.
In Esteli, Las Segovias, Nicaragua, the frequency of isolations of enteropathogenic (EPEC), and enterotoxigenic E. coli (ETEC) was investigated in 100 children with (n = 50) and without diarrhoea (n = 50). EPEC was found to be significantly (p < 0.05) more frequent in diarrhoeal (16%) than in healthy children (4%). Detailed analyses revealed that 6 serotypes of E. coli were involved. Isolation of ETEC was not statistically significantly different (p > 0.05) in diarrhoeal (28%) and healthy children (16%). Determination of the susceptibility of isolated E. coli indicated a high level of resistance to common antimicrobial drugs. These resistant strains of E. coli might become a health problem in this part of Nicaragua.
在尼加拉瓜拉斯塞戈维亚斯的埃斯特利，对100名腹泻儿童（n = 50）和非腹泻儿童（n = 50）进行了调查，以研究肠道致病性大肠杆菌（EPEC）和产肠毒素大肠杆菌（ETEC）的分离频率。结果发现，腹泻儿童中EPEC的分离频率（16%）显著高于健康儿童（4%）（p < 0.05）。详细分析表明，涉及6种大肠杆菌血清型。腹泻儿童（28%）和健康儿童（16%）中ETEC的分离率在统计学上无显著差异（p > 0.05）。对分离出的大肠杆菌进行药敏测定表明，其对常用抗菌药物具有高度耐药性。这些耐药大肠杆菌菌株可能会在尼加拉瓜的这一地区引发健康问题。
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