Mannweiler E, Mohr W, Höfler W, Lederer I
Dtsch Med Wochenschr. 1976 Dec 24;101(52):1915-9. doi: 10.1055/s-0028-1104355.
Tests for serum antibodies against two amoeba antigens were performed on serum samples from 70 patients with amoebic liver abscesses, 204 travellers returning from tropical countries and 136 inhabitants of an endemic region without evidence of amoebiasis. Suspicious or borderline results in the complement-fixation, indirect haemagglutination, latex-agglutination, and double-gel diffusion tests occurred in 73.3%-90.4% of patients with amoebic liver abscess, in the same reactions (except double-gel diffusion test) in 12.1-18.9% of travellers in the trophics, and 16.2%-46.3% of inhabitants of endemic regions. There was evidence for the need of performing several tests: patients with amoebic liver abscesses gave diagnostically useful results the more frequently the more tests were performed on a given serum sample. Negative results in the three tests occurred in only one case of multiple liver abscesses, but the sample had been obtained very early.
对70例阿米巴肝脓肿患者、204名从热带国家归来的旅行者以及136名来自流行区但无阿米巴病证据的居民的血清样本进行了针对两种阿米巴抗原的血清抗体检测。在阿米巴肝脓肿患者中，补体结合试验、间接血凝试验、乳胶凝集试验和双向凝胶扩散试验出现可疑或临界结果的比例为73.3%-90.4%；在热带地区的旅行者中，同样的反应（双向凝胶扩散试验除外）出现可疑或临界结果的比例为12.1%-18.9%；在流行区居民中，这一比例为16.2%-46.3%。有证据表明需要进行多项检测：对给定血清样本进行的检测越多，阿米巴肝脓肿患者获得诊断有用结果的频率就越高。三项检测结果均为阴性的情况仅在1例多发性肝脓肿患者中出现，但该样本采集时间很早。
