黑腹果蝇中多巴脱羧酶的遗传学。I. 缺失多巴脱羧酶剂量敏感区域和α-甲基多巴超敏位点的缺陷型的分离与特性分析。
The genetics of dopa decarboxylase in Drosophila melanogaster. I. Isolation and characterization of deficiencies that delete the dopa-decarboxylase-dosage-sensitive region and the alpha-methyl-dopa-hypersensitive locus.
作者信息
Wright T R, Hodgetts R B, Sherald A F
出版信息
Genetics. 1976 Oct;84(2):267-85. doi: 10.1093/genetics/84.2.267.
Abstract
A detailed cytogenetic investigation of 16 overlapping deficiencies in the 36C-40A region on the left arm of the second chromosome (2L) in Drosophila melanogaster is reported. These deficiencies permit a localization of both the dopa-decarboxylase-dosage-sensitive region and the alpha-methyl-dopa-hypersensitive locus, l(2) amd, to the same region, 37B10-37C7.
摘要
报道了对黑腹果蝇第二染色体（2L）左臂36C - 40A区域内16个重叠缺失进行的详细细胞遗传学研究。这些缺失使得多巴脱羧酶剂量敏感区域和α - 甲基多巴超敏位点l(2)amd都定位到了同一区域，即37B10 - 37C7。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
[on tyrosine metabolism by insects. VII. The catabolic decomposition of tyrosine and the biogenesis of the sclerotizing substance, N-acetyldopamine].[关于昆虫的酪氨酸代谢。VII. 酪氨酸的分解代谢及硬化物质N-乙酰多巴胺的生物合成]
Biochim Biophys Acta. 1962 Jul 30;62:103-13. doi: 10.1016/0006-3002(62)90495-x.
3
[On tyrosine metabolism in insects. XVII. The tyrosine metabolism of Tenebrie molitor and Drosophila melanogaster].
Hoppe Seylers Z Physiol Chem. 1966;344(4):267-75.
4
The metabolism of tyrosine-O-phosphate in Drosophila.果蝇中磷酸酪氨酸的代谢
Arch Biochem Biophys. 1969 Jul;132(2):450-6. doi: 10.1016/0003-9861(69)90388-9.
5
Ecdysone, an insect steroid hormone, and its mode of action.蜕皮激素，一种昆虫甾体激素，及其作用方式。
Recent Prog Horm Res. 1966;22:473-502. doi: 10.1016/b978-1-4831-9825-5.50015-4.
6
Segmental aneuploidy and the genetic gross structure of the Drosophila genome.节段性非整倍体与果蝇基因组的遗传总体结构。
Genetics. 1972 May;71(1):157-84. doi: 10.1093/genetics/71.1.157.
7
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Anal Biochem. 1972 Jan;45(1):242-52. doi: 10.1016/0003-2697(72)90024-3.
8
Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses.果蝇中酶活性的调控。I. 通过基因剂量反应检测调控位点。
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9
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10
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Mol Gen Genet. 1974 May 21;130(2):127-41. doi: 10.1007/BF00269084.
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