Sakuma I, Fukui Y, Ohara Y, Makinouchi K, Takatani S, Nosé Y
Department of Applied Electronic Engineering, Tokyo Denki University, Japan.
ASAIO J. 1993 Jul-Sep;39(3):M433-7.
To design a less hemolytic and more antithrombogenic centrifugal blood pump, secondary flow, i.e., vortex and turbulent flow, must be properly controlled. An irregular stream pattern is a cause of hemolysis, and good wash-out around the shaft minimizes thrombus formation. In this study, flow visualization methods were applied to evaluate secondary flow in a centrifugal blood pump. Correlation with results of in vitro hemolysis tests was investigated. Separation of the stream lines from the vanes and patterns implying the existence of vortices were observed in the impeller that showed high hemolysis. By adjustment of vane angles, these irregular patterns could be minimized, and hemolysis decreased as well. Using a similar technique, the flow pattern at the back of the impeller could be visualized, which enabled further investigation of the effects of secondary flow on thrombus formation. This flow visualization was effective in examining secondary flow patterns.
为设计一种溶血作用较小且抗血栓形成能力更强的离心式血泵，必须妥善控制二次流，即涡流和紊流。不规则的流型是溶血的一个原因，而轴周围良好的冲洗作用可将血栓形成降至最低。在本研究中，应用流动可视化方法来评估离心式血泵中的二次流。研究了其与体外溶血试验结果的相关性。在显示出高溶血率的叶轮中观察到流线与叶片分离以及意味着存在涡流的流型。通过调整叶片角度，这些不规则流型可减至最小，溶血也会降低。使用类似技术，可以使叶轮背面的流型可视化，从而能够进一步研究二次流对血栓形成的影响。这种流动可视化对于检查二次流型很有效。
