Ohara Y, Murase M, Nosé Y
Department of Thoracic Surgery, Nagoya University School of Medicine, Japan.
Artif Organs. 1997 Jul;21(7):694-9. doi: 10.1111/j.1525-1594.1997.tb03725.x.
The hemolytic effect of the secondary vane system, the antithrombogenic structure incorporated into the back side of the impeller of the C1E3 Gyro pump, was investigated. Impellers with 0, 2, 3, and 4 secondary vanes and an additional impeller with 2 secondary channels were fabricated and incorporated into the C1E3 pump casings. Hemolysis tests were performed under cardiopulmonary bypass conditions (flow rate 4.5 L/min, total pressure head 350 mm Hg) using flesh bovine blood. The normalized indices of hemolysis (NIH) of the pumps with 0, 2, 3, and 4 secondary vanes and the pump with 2 secondary channels were 0.0797, 0.0866, 0.104, 0.157, and 0.0591, respectively. These results indicated that design of the impeller with 2 secondary channels, which was the original design of C1E3 Gyro pump, was less hemolytic than the design with secondary vanes. Additionally, the possibility of the secondary channel system for the impeller bottom was demonstrated favorably.
研究了C1E3陀螺泵叶轮背面的抗血栓形成结构——次级叶片系统的溶血作用。制作了带有0、2、3和4个次级叶片的叶轮，以及一个带有2个次级通道的额外叶轮，并将其安装到C1E3泵壳中。在体外循环条件下（流速4.5L/min，总压头350mmHg）使用新鲜牛血进行溶血试验。带有0、2、3和4个次级叶片的泵以及带有2个次级通道的泵的标准化溶血指数（NIH）分别为0.0797、0.0866、0.104、0.157和0.0591。这些结果表明，C1E3陀螺泵的原始设计——带有2个次级通道的叶轮设计比带有次级叶片的设计溶血更少。此外，叶轮底部采用次级通道系统的可能性也得到了有力证明。
