Bloom J A, Frank J W, Shafir M S, Martiquet P
Department of Family and Community Medicine, University of Toronto.
Can Fam Physician. 1993 Nov;39:2337-45.
Forty-seven patients older than 65 years were randomly selected for structured chart review of all long-term medications documented during the prior year and the number of instances of potentially undesirable prescribing for each patient. A trained nurse subsequently made home visits to assess all long-term medications used regularly during the same period. Forty-five percent of elderly patients had one or more instances of potentially undesirable drug use, all of which appeared to be readily remediable. Commercial drug interaction software identified less than half of the potentially undesirable instances.
随机选取了47名65岁以上的患者,对他们前一年记录的所有长期用药情况以及每位患者潜在不当处方的实例数量进行结构化图表审查。随后,一名经过培训的护士进行家访,以评估同期定期使用的所有长期药物。45%的老年患者有一个或多个潜在不当用药实例,所有这些似乎都易于纠正。商业药物相互作用软件识别出的潜在不当实例不到一半。