Roberge R F, Genest A, Beauchemin J P, Parent M
Unité de recherche en gériatrie de l'Université Laval.
Can Fam Physician. 1995 May;41:800-5.
To evaluate the incidence of benzodiazepine overprescription as a cause of benzodiazepine overuse in nursing homes. DESIGN AND SETTING: Physicians were asked to complete a multiple-choice questionnaire for patients receiving at least one benzodiazepine and to indicate the reason for the prescription. To control for social desirability bias, two fictitious cases were submitted to each physician. Overprescription was defined as a prescription for benzodiazepine that differed from the indications given in the product monograph. PARTICIPANTS: Family physicians of patients living in three nursing homes in the Quebec City area were solicited by mail to take part in the survey. RESULTS: Fifteen physicians treating 152 patients, whose average age was 82.1 years (range 50 to 100 years), agreed to take part in the study. It was found that 77.1% of the patients had been taking a benzodiazepine for more than a year. For 14.5% of the prescriptions, there was no official indication. The reasons most frequently cited for these prescriptions were that the physician was renewing a prescription given before he took charge of the patient, the patient's refusal to discontinue use of the medication, pressure from the nursing staff, and the fact that the patient was causing a disturbance. In 4% of the cases (6 answers), the physician acknowledged that there was no indication for prescribing a benzodiazepine. CONCLUSION: This study shows that, in 14.5% of cases, overprescription could be a cause of benzodiazepine overuse in nursing homes.
评估苯二氮䓬类药物过度处方作为养老院中苯二氮䓬类药物过度使用原因的发生率。
要求医生为至少服用一种苯二氮䓬类药物的患者填写一份多项选择题问卷,并指出处方原因。为控制社会期望偏差,向每位医生提交了两个虚构病例。过度处方定义为与产品说明书中给出的适应症不同的苯二氮䓬类药物处方。
通过邮件邀请魁北克市地区三家养老院患者的家庭医生参与调查。
15名医生治疗152名患者,患者平均年龄82.1岁(范围50至100岁),同意参与研究。发现77.1%的患者服用苯二氮䓬类药物超过一年。14.5%的处方无官方适应症。这些处方最常被提及的原因是医生续签其负责该患者之前开具的处方、患者拒绝停药、护理人员的压力以及患者造成干扰。在4%的病例(6份回答)中,医生承认开具苯二氮䓬类药物没有适应症。
本研究表明,在14.5% 的病例中,过度处方可能是养老院中苯二氮䓬类药物过度使用的一个原因。