Lowe G
Psychopharmacology (Berl). 1976 Jul 28;48(2):233-4. doi: 10.1007/BF00423266.
The effect of the anti-psychotic drug, haloperidol (50 mg/kg), on bar pressing in the rat was investigated in a light-reinforcement situation. Drugged animals responded significantly more for response contingent flickering light (RCF) and less for steady light (RCL) than saline injected animals. The finding is consistent with the possible arousal decreasing action of haloperidol and with the notion of an optimum level of arolsal.
在光照强化条件下,研究了抗精神病药物氟哌啶醇(50毫克/千克)对大鼠压杆行为的影响。与注射生理盐水的动物相比,用药动物对反应偶联闪烁光(RCF)的反应显著更多,而对稳定光(RCL)的反应更少。这一发现与氟哌啶醇可能的唤醒降低作用以及最佳唤醒水平的概念相一致。