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[原发性干燥综合征的流行病学研究]

[Epidemiological studies on primary Sjogren's syndrome].

作者信息

Zhang N Z, Shi Q S, Yao Q P

机构信息

Peking Union Medical College Hospital, Beijing.

出版信息

Zhonghua Nei Ke Za Zhi. 1993 Aug;32(8):522-4.

PMID:8269779
Abstract

2,066 adult people of a Beijing suburb village were surveyed for primary Sjogren's syndrome, using questionnaire and serological tests in each case as the primary screening tool. 16 cases were discovered by Copenhagen criteria indicating a prevalence rate of 0.77% and 7 cases with a prevalence rate of 0.33% by Fox criteria. Similar study was done in 100 non-connective tissue diseases in-patients. 4 cases were discovered by Copenhagen criteria and one case by Fox criteria. In 126 definite cases of primary Sjogren's syndrome, the longest time interval between first onset of symptoms and firm establishment of diagnosis was 20 years with an average of 7.8 years indicating most cases were wrongly diagnosed or highly neglected.

摘要

对北京郊区一个村庄的2066名成年人进行了原发性干燥综合征的调查,采用问卷和血清学检测作为初步筛查工具。根据哥本哈根标准发现16例,患病率为0.77%;根据福克斯标准发现7例,患病率为0.33%。对100例非结缔组织病住院患者进行了类似研究。根据哥本哈根标准发现4例,根据福克斯标准发现1例。在126例原发性干燥综合征确诊病例中,症状首次出现到确诊的最长时间间隔为20年,平均为7.8年,这表明大多数病例被误诊或被严重忽视。

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