Grewal R P
National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Int J Psychiatry Med. 1993;23(3):307-12. doi: 10.2190/JKFW-3WXK-QA7N-BYLN.
To determine the frequency and etiology of psychiatric complications in patients with Fabry's disease. Method-Retrospective analysis and review of the records of thirty-three patients with confirmed Fabry's disease.
Six patients (18%) developed psychiatric disorders. Five patients suffered depression and two of these patients committed suicide. One patient developed an acute confusional episode with subsequent development of behavioral changes as a complication of cerebrovascular disease.
Psychiatric disorders, most commonly depression, complicate Fabry's disease and contribute to the morbidity and mortality of this disease.
确定法布里病患者精神并发症的发生率及病因。方法——对33例确诊为法布里病患者的记录进行回顾性分析和审查。
6例患者（18%）出现精神障碍。5例患者患有抑郁症，其中2例自杀。1例患者因脑血管疾病并发症出现急性意识模糊发作，随后出现行为改变。
精神障碍，最常见的是抑郁症，使法布里病复杂化，并导致该疾病的发病率和死亡率上升。
