Reed L, Willison C D, Schochet S S, Voelker J L
Department of Pathology, West Virginia University School of Medicine, Morgantown.
J Neurosurg. 1994 Jan;80(1):148-51. doi: 10.3171/jns.1994.80.1.0148.
A giant cell tumor involving the vertex of the skull is described in a 3-year-old child with no history of head trauma. The mass was present approximately 4 months prior to resection. Microscopically, the lesion consisted of highly cellular tissue composed of oval to spindle-shaped stromal cells admixed with numerous multinucleated giant cells. Giant cell tumor of the skull is a rare lesion, usually involving the sphenoid or temporal bone in adults. The differential diagnosis is discussed with reference to the literature regarding giant cell lesions, especially of the cranium. The authors are unaware of previous reports of a similar lesion in this location in such a young child.
本文描述了一名3岁儿童，其颅骨顶部出现巨细胞瘤，无头部外伤史。肿块在切除前约4个月出现。显微镜下，病变由高度细胞化组织构成，该组织由椭圆形至梭形的基质细胞以及大量多核巨细胞混合组成。颅骨巨细胞瘤是一种罕见病变，在成人中通常累及蝶骨或颞骨。本文结合有关巨细胞病变尤其是颅骨巨细胞病变的文献对鉴别诊断进行了讨论。作者未发现此前有关于如此年幼的儿童在此部位出现类似病变的报道。
