Hörner M
Dermatologischen Abteilung, Krankenanstalt Rudolfstiftung, Wien.
Wien Med Wochenschr. 1993;143(16-17):464-8.
Interferons (IFN) provide a systemic alternative for the therapy of human papillomavirus (HPV) induced anogenital warts. Local therapy cannot totally eliminate latent viral genome in the perilesional epithelium. This causes the danger of new exacerbations. Reviewing different reports and by own therapeutic experience we think, that IFN treatment may be successful in combination with local therapy and for pre-surgical diminution of extended condyloma. Sufficient dose is necessary. Poor effects are to be expected if the warts lasted for longer than 12 months and in case of severe immunodeficiency.
干扰素（IFN）为治疗人乳头瘤病毒（HPV）引起的肛门生殖器疣提供了一种全身性替代疗法。局部治疗无法完全消除病灶周围上皮中的潜伏病毒基因组。这会导致新的病情加重的风险。通过回顾不同的报告并结合我们自己的治疗经验，我们认为，干扰素治疗与局部治疗联合使用以及在手术前缩小广泛的尖锐湿疣可能会取得成功。需要足够的剂量。如果疣体持续超过12个月以及在严重免疫缺陷的情况下，预计效果不佳。
