Fowler W C, Hoffman J P, Eisenberg B L
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111.
World J Surg. 1993 Sep-Oct;17(5):658-61; discussion 661-2. doi: 10.1007/BF01659136.
Redo hepatic resection for recurrent colorectal metastasis was performed in eight patients. There was no operative mortality; major morbidity occurred in 25% and minor morbidity in 13% of patients. Four patients are alive and disease-free at 9, 23, 39, and 49 months, respectively, after their repeat hepatic resection. Four patients have died of recurrent disease, with a median time to recurrence of 6 months and median survival of 15 months. Patterns of failure include hepatic failure alone in two patients and pulmonary and hepatic failure in two. Repeat liver resection can be performed safely and may be beneficial in some patients with recurrent metastases confined to the liver after previous hepatic metastasectomy.
8例患者接受了复发性结直肠癌肝转移的再次肝切除手术。无手术死亡病例；25%的患者发生了严重并发症，13%的患者发生了轻微并发症。4例患者在再次肝切除术后分别于9个月、23个月、39个月和49个月存活且无疾病复发。4例患者死于复发性疾病，复发的中位时间为6个月，中位生存期为15个月。失败模式包括2例仅出现肝衰竭，2例出现肺和肝衰竭。再次肝切除可以安全地进行，对于一些先前肝转移切除术后肝内复发转移局限的患者可能有益。
