Benya E C, Sivit C J, Quinones R R
Department of Diagnostic Imaging, Children's National Medical Center, Washington, DC 20010.
AJR Am J Roentgenol. 1993 Nov;161(5):1023-7. doi: 10.2214/ajr.161.5.8273603.
Bone marrow transplantation is increasingly used in children to treat refractory malignant neoplasms, immunodeficiency syndromes, and hematopoietic and genetic disorders. In preparation for the transplantation, patients receive high doses of chemotherapeutic agents and total-body irradiation to destroy residual malignant cells or dysfunctional marrow and to prevent rejection of the graft. A variety of abdominal and pelvic complications may occur after transplantation because of pancytopenia, the direct toxic effects of the preparative regimen, graft-vs-host disease, or immunosuppression. This essay illustrates the CT and sonographic appearances of these complications.
骨髓移植在儿童中越来越多地用于治疗难治性恶性肿瘤、免疫缺陷综合征以及造血和遗传性疾病。在移植准备过程中,患者接受高剂量的化疗药物和全身照射,以破坏残留的恶性细胞或功能失调的骨髓,并防止移植物排斥。由于全血细胞减少、预处理方案的直接毒性作用、移植物抗宿主病或免疫抑制,移植后可能会出现各种腹部和盆腔并发症。本文阐述了这些并发症的CT和超声表现。