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儿童骨髓移植后的腹部并发症:超声和CT表现

Abdominal complications after bone marrow transplantation in children: sonographic and CT findings.

作者信息

Benya E C, Sivit C J, Quinones R R

机构信息

Department of Diagnostic Imaging, Children's National Medical Center, Washington, DC 20010.

出版信息

AJR Am J Roentgenol. 1993 Nov;161(5):1023-7. doi: 10.2214/ajr.161.5.8273603.

DOI:10.2214/ajr.161.5.8273603
PMID:8273603
Abstract

Bone marrow transplantation is increasingly used in children to treat refractory malignant neoplasms, immunodeficiency syndromes, and hematopoietic and genetic disorders. In preparation for the transplantation, patients receive high doses of chemotherapeutic agents and total-body irradiation to destroy residual malignant cells or dysfunctional marrow and to prevent rejection of the graft. A variety of abdominal and pelvic complications may occur after transplantation because of pancytopenia, the direct toxic effects of the preparative regimen, graft-vs-host disease, or immunosuppression. This essay illustrates the CT and sonographic appearances of these complications.

摘要

骨髓移植在儿童中越来越多地用于治疗难治性恶性肿瘤、免疫缺陷综合征以及造血和遗传性疾病。在移植准备过程中,患者接受高剂量的化疗药物和全身照射,以破坏残留的恶性细胞或功能失调的骨髓,并防止移植物排斥。由于全血细胞减少、预处理方案的直接毒性作用、移植物抗宿主病或免疫抑制,移植后可能会出现各种腹部和盆腔并发症。本文阐述了这些并发症的CT和超声表现。

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Abdominal complications after bone marrow transplantation in children: sonographic and CT findings.儿童骨髓移植后的腹部并发症:超声和CT表现
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2
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Analysis of incidence and risk factors of the multidrug resistant gastrointestinal tract infection in children and adolescents undergoing allogeneic and autologous hematopoietic cell transplantation: a nationwide study.分析儿童和青少年接受异基因和自体造血细胞移植后多重耐药胃肠道感染的发生率和危险因素:一项全国性研究。
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CT in the clinical and prognostic evaluation of acute graft-vs-host disease of the gastrointestinal tract.
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Br J Radiol. 2012 Aug;85(1016):e416-23. doi: 10.1259/bjr/60038597. Epub 2011 Nov 29.
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Curr Gastroenterol Rep. 2010 Aug;12(4):249-58. doi: 10.1007/s11894-010-0112-5.
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Gastrointestinal complications following hematopoietic stem cell transplantation in children.儿童造血干细胞移植后的胃肠道并发症
Korean J Radiol. 2008 Sep-Oct;9(5):449-57. doi: 10.3348/kjr.2008.9.5.449.
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Rectal inflammation as first manifestation of graft-vs-host disease: radiologic-pathologic findings.
Eur Radiol. 2003 Dec;13 Suppl 6:L75-8. doi: 10.1007/s00330-002-1801-8. Epub 2003 Jan 17.
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Venoocclusive disease of the liver following renal transplantation.
Dig Dis Sci. 1998 Feb;43(2):229-34. doi: 10.1023/a:1018873415221.
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