Segatore M, Jacobs M
Axone. 1993 Dec;15(2):34-9.
Seizures after traumatic brain injury may cause acute deterioration in level of consciousness, signal the presence of significant intracranial pathology, herald potentially lethal status epilepticus and carry some risk for the development of a chronic disorder. Specific implications of immediate, early and late seizures are different and vary across age groups. While there is a consensus to manage status epilepticus aggressively, and some agreement to treat a seizure once it has begun, no such unanimity exists about management of patients who have one or more seizures after injury. This article identifies controversies about seizures that occur after traumatic brain injury in paediatric and adult populations. It concludes with a summary of research imperatives for the future.
创伤性脑损伤后的癫痫发作可能导致意识水平急性恶化,提示存在严重的颅内病变,预示可能致命的癫痫持续状态,并具有引发慢性疾病的一些风险。即刻、早期和晚期癫痫发作的具体影响不同,且因年龄组而异。虽然对于积极处理癫痫持续状态存在共识,对于癫痫发作一旦开始进行治疗也有一定的共识,但对于受伤后有一次或多次癫痫发作的患者的管理却没有这样的一致意见。本文确定了儿科和成人人群创伤性脑损伤后癫痫发作的争议点。最后总结了未来的研究重点。