Mielants H, Veys E M, Maertens M, Goemaere S, De Clercq L, Castro S, Praet J
Department of Rheumatology, University of Ghent, Belgium.
Clin Exp Rheumatol. 1993 Sep-Oct;11(5):563-7.
In order to determine the prevalence of inflammatory rheumatic diseases in an urban secondary school student population, a questionnaire dealing with past or present joint, tendon, axial, gastrointestinal, ocular and dermatological symptoms was completed by 2,990 students of secondary schools in Antwerp and Ghent. The parents were asked to complete a questionnaire regarding the family medical history. From these 2,990 students, 524 were selected for further investigation by a rheumatology resident, who checked the answers to the first questionnaire and performed a clinical examination. Forty-one adolescents with a presumptive history or present symptoms of inflammatory rheumatic diseases were retained. These students were examined by the medial staff of the rheumatology department; if necessary, a complementary biochemical and radiological examination was performed. Five cases of definite juvenile chronic arthritis (JCA) (with polyarticular onset in 1 case and late pauciarticular onset in 4 cases) and 4 cases of presumptive late pauciarticular onset JCA were detected, resulting in a prevalence of 167 per 100,000 for definite JCA and of 301 per 100,000 for possible JCA. This prevalence rate is higher than that generally described. This method of investigation effectively allows the detection of milder and spontaneously remitting cases of JCA. It further enabled us to definite case and 4 presumptive cases of various previously undiagnosed forms of JCA.
为了确定城市中学生人群中炎性风湿性疾病的患病率，安特卫普和根特的中学2990名学生完成了一份关于过去或现在关节、肌腱、轴向、胃肠道、眼部和皮肤症状的问卷。同时要求家长填写一份关于家族病史的问卷。从这2990名学生中，524名学生被风湿病住院医师挑选出来做进一步调查，该医师检查了第一份问卷的答案并进行了临床检查。41名有炎性风湿性疾病既往史或现有症状的青少年被保留下来。这些学生由风湿病科的医疗人员进行检查；必要时，进行补充生化和放射学检查。检测出5例确诊的幼年慢性关节炎（JCA）（1例多关节起病，4例晚少关节起病）和4例疑似晚少关节起病JCA，确诊JCA的患病率为每10万人167例，可能JCA的患病率为每10万人301例。这一患病率高于一般描述的患病率。这种调查方法有效地检测出了病情较轻且能自发缓解的JCA病例。它还使我们能够确定各种先前未确诊的JCA确诊病例和4例疑似病例。
