Moe N, Rygg M
Department of Pediatrics, University of Tromsø, Norway.
Clin Exp Rheumatol. 1998 Jan-Feb;16(1):99-101.
To study the incidence and prevalence of juvenile chronic arthritis (JCA) in northern Norway.
Cases from the period 1985-1994 were retrospectively identified from the hospital files of the only pediatric department treating JCA in the study area. The European League Against Rheumatism (EULAR) criteria for JCA were used.
The annual incidence of JCA was 22.6/100,000 children under 16 years of age. The incidence of oligoarticular JCA was 11.8, and the incidence of systemic JCA was 0.8/100,000. In the incidence group 25% were ANA positive, 14% developed uveitis and 42% of the tested patients were HLA-B27 positive. The point prevalence was 148.1/100,000.
These incidence and prevalence data are higher than those reported in most other studies. The impact of genetic differences, cyclic variations and other factors in relation to the onset and course of JCA merit further investigation.
研究挪威北部青少年慢性关节炎(JCA)的发病率和患病率。
回顾性地从研究区域内唯一一家治疗JCA的儿科部门的医院档案中确定1985年至1994年期间的病例。采用欧洲抗风湿病联盟(EULAR)的JCA标准。
JCA的年发病率为每10万名16岁以下儿童中有22.6例。少关节型JCA的发病率为11.8,全身型JCA的发病率为每10万中有0.8例。在发病组中,25%的患者抗核抗体(ANA)呈阳性,14%的患者出现葡萄膜炎,42%的受试患者人类白细胞抗原B27(HLA - B27)呈阳性。点患病率为每10万中有148.1例。
这些发病率和患病率数据高于大多数其他研究报告的数据。基因差异、周期性变化及其他与JCA发病和病程相关的因素的影响值得进一步研究。