Weglage J, Fünders B, von Teeffelen-Heithoff A, Ullrich K
Klinik und Poliklinik für Kinderheilkunde-Allgemeine Kinderheilkunde, Universität Münster/Westf.
Fortschr Med. 1993 Nov 10;111(31):485-8.
Recent results of research appear to show that over the past few years, clearly more restrictive dietary recommendations have become accepted in the treatment of phenylketonuria (PKU). A lifelong diet low in phenylalanine is the goal, since poor dietary discipline can lead to an appreciable decrease in the level of intelligence and, in rare cases, to severe neurological deficits. Furthermore, neuropsychological symptoms as sequelae of current high serum phenylalanine levels also occur. In the present study, the question as to the development of intelligence and compliance with diet was investigated. The results underscore the need for continuing adherence to a diet on the one hand, and for continuous psychosocial support on the other.
最近的研究结果似乎表明，在过去几年中，在苯丙酮尿症（PKU）的治疗中，明显更为严格的饮食建议已被接受。目标是终身食用低苯丙氨酸饮食，因为饮食控制不佳会导致智力水平明显下降，在极少数情况下还会导致严重的神经功能缺损。此外，当前高血清苯丙氨酸水平的后遗症还会出现神经心理症状。在本研究中，对智力发育和饮食依从性问题进行了调查。结果强调一方面需要持续坚持饮食，另一方面需要持续的社会心理支持。
