Wijers E R, Zijlstra C, Lenstra J A
Institute of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands.
Genomics. 1993 Oct;18(1):113-7. doi: 10.1006/geno.1993.1433.
The major satellite of the horse genome consists of about 1 million copies of a 221-bp tandem repeat unit. By fluorescence in situ hybridization it has been localized in the centromeres of 58 of the 64 horse chromosomes. The donkey genome contains a similar but not identical satellite. Strikingly, the equine repeat did not hybridize to DNA of the Grevy zebra, despite the divergence of the horse and zebra only 3 to 5 million years ago and the ability of these species to crossbreed. The evolution of satellite DNA in the Equidae is more rapid than that in other mammalian families, which may be explained by their rapid karyotypic evolution.
马基因组的主要卫星DNA由约100万个221碱基对的串联重复单元组成。通过荧光原位杂交技术,它已定位在64条马染色体中58条的着丝粒上。驴基因组包含一种相似但并不相同的卫星DNA。引人注目的是,尽管马和细纹斑马在仅300万至500万年前就已分化,且这些物种有杂交能力,但马的重复序列并未与细纹斑马的DNA杂交。马科动物卫星DNA的进化比其他哺乳动物家族更快,这可能是由它们快速的核型进化所解释的。