Fawcett J
Department of Psychiatry, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
Int Clin Psychopharmacol. 1993 Winter;8(4):217-20. doi: 10.1097/00004850-199300840-00002.
Clinical depression is associated with social, occupational and physical impairment and mortality. Furthermore, data are reviewed which have related the severity of depressive symptoms, such as anhedonia, psychic anxiety, panic attacks, alcohol abuse, insomnia and diminished concentration in depressed patients, to suicide within 1 year. By contrast, hopelessness, suicidal ideation, and prior suicide attempts were related to suicide within 2-10 years after examination, but did not correlate with suicide within the first year of follow-up. It is concluded that clinical depression continues to be associated with significant morbidity and mortality, despite progress which has been made in its treatment.
临床抑郁症与社会、职业和身体损害以及死亡率相关。此外，还对一些数据进行了综述，这些数据将抑郁症状的严重程度，如快感缺失、精神焦虑、惊恐发作、酒精滥用、失眠以及抑郁症患者注意力不集中等，与1年内的自杀行为联系起来。相比之下，绝望感、自杀意念和既往自杀未遂与检查后2至10年内的自杀行为相关，但与随访第一年的自杀行为无关。结论是，尽管在抑郁症治疗方面取得了进展，但临床抑郁症仍然与显著的发病率和死亡率相关。
