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断乳期恒河猴缺铁性贫血的患病率及危险因素

Prevalence and risk factors for iron deficiency anemia in weanling rhesus macaques.

作者信息

Bicknese E J, George J W, Hird D W, Paul-Murphy J, Anderson J A, Roberts J R

机构信息

Veterinary Services, San Diego Zoo, CA 92112.

出版信息

Lab Anim Sci. 1993 Oct;43(5):434-8.

PMID:8277722
Abstract

Standard epidemiologic methods were used to determine the prevalence and risk factors for iron deficiency at weaning in 143 weanling rhesus macaques (Macaca mulatta) raised indoors at the California Primate Research Center, Davis, CA. Maternal, infant, and management factors were investigated. Prevalence of iron deficiency anemia was 19%, as defined by mean corpuscular volume less than or equal to 66 femtoliters. It was found that animals raised entirely or partially in the nursery had less iron deficiency than dam-reared offspring. Results also suggest multiparous dams were more likely to have iron-deficient weanlings than primiparous dams. These results were discussed in relation to human and nonhuman primate pediatric medicine.

摘要

采用标准流行病学方法,对加利福尼亚大学戴维斯分校灵长类动物研究中心室内饲养的143只断奶恒河猴(猕猴)断奶时缺铁的患病率及风险因素进行了测定。对母体、婴儿及管理因素进行了调查。根据平均红细胞体积小于或等于66飞升来定义,缺铁性贫血的患病率为19%。研究发现,完全或部分在育婴室饲养的动物比由母猴抚养的后代缺铁情况更少。结果还表明,经产母猴比初产母猴更有可能产出缺铁的断奶幼猴。结合人类和非人类灵长类动物儿科学对这些结果进行了讨论。

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