Andreasen N C, Harris G, Cizadlo T, Arndt S, O'Leary D S, Swayze V, Flaum M
Mental Health Clinical Research Center, College of Medicine, University of Iowa Hospitals and Clinics, Iowa City 52242.
Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):93-7. doi: 10.1073/pnas.91.1.93.
A method for measuring sulcal and gyral patterns, using data derived from magnetic resonance (MR) scanning, is described. This method can be applied through two newly developed computer programs, BRAINPLOT and BRAINMAP. These programs provide quantitative measures of brain surface pattern. The method has been validated with postmortem brains, phantoms, and human MR data. The method is robust to detecting differences in brain surface anatomy between atrophic and nonatrophic brains. It appears to offer an efficient, fully automated, and accurate method for analyzing the large amounts of information generated through in vivo neuroimaging techniques.
描述了一种利用磁共振(MR)扫描数据测量脑沟和脑回模式的方法。该方法可通过两个新开发的计算机程序BRAINPLOT和BRAINMAP来应用。这些程序提供脑表面模式的定量测量。该方法已在尸检脑、模型和人类MR数据上得到验证。该方法在检测萎缩性和非萎缩性脑之间的脑表面解剖差异方面具有鲁棒性。它似乎为分析通过体内神经成像技术生成的大量信息提供了一种高效、全自动且准确的方法。