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一项关于¹³¹I标记的甲状腺激素在猪组织中定位的放射自显影研究。

An autoradiographic study on the localization of 131I-labeled thyroid hormones in the tissues of the pig.

作者信息

Prakash P, St Clair L E, Romack F E

出版信息

Anat Anz. 1976;139(4):321-31.

PMID:984433
Abstract

Autoradiographic studies on the localization of 131I-labeled thyroxine and triiodothyronine in the various organs and tissues of the pig have been conducted. The isotopes were compared as to the intensity of radioactivity on the basis of the concentration of developed silver grains in the tissues following the respective radioactive hormone injections. In general, for an identical dose of the isotope and with analogous processing procedures, the autoradiographs of most of the tissues after triiodothyronine were relatively more radioactive than after thyroxine. In both the hormone treatments, the tissues from younger pigs were relatively more radioactive than the tissues of older pigs. The various tissormones. Based on differential localization of radioactivity, the pigs excreted more radioiodine through bile, pancreatic and salivary secretions and in urine.

摘要

已经对131I标记的甲状腺素和三碘甲状腺原氨酸在猪的各种器官和组织中的定位进行了放射自显影研究。根据在分别注射放射性激素后组织中显影银粒的浓度,对同位素的放射性强度进行了比较。一般来说,对于相同剂量的同位素和类似的处理程序,大多数组织在注射三碘甲状腺原氨酸后的放射自显影片的放射性相对高于注射甲状腺素后的。在两种激素处理中,幼猪的组织放射性相对高于成年猪的组织。根据放射性的差异定位,猪通过胆汁、胰腺和唾液分泌物以及尿液排出更多的放射性碘。

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