Vernant P, Gaudeau S, Tillement J P, Derrida J P
Arch Mal Coeur Vaiss. 1976 Oct;69(10):1067-71.
High-output states combining tachycardia, increased cardiac output and raised blood pressure are often seen in clinical practice with causes other than the classical ones (hyperthyroidism anaemia and arterio-venous fistulae). Noticing how these syndromes ressemble cardiac beri-beri, the authors looked for hypothiaminaemia in these patients. On the 25 cases studied, two were particularly interesting as there was frank hypothiaminaemia, and also as treatment with vitamin B1 corrected not only the biochemical disorder but also the clinical symptoms, and led to lessening of the trachyardia and a reduction in cardiac output and blood pressure.
高输出量状态合并心动过速、心输出量增加和血压升高在临床实践中经常可见，其病因并非经典的那些（甲状腺功能亢进、贫血和动静脉瘘）。由于注意到这些综合征与心脏型脚气病相似，作者对这些患者进行了低硫胺血症的检查。在所研究的25例病例中，有两例特别有意思，因为存在明显的低硫胺血症，而且维生素B1治疗不仅纠正了生化紊乱，还改善了临床症状，使心动过速减轻，心输出量和血压降低。
