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结膜自体移植术在翼状胬肉手术治疗中的应用

Conjunctival autografting in the surgical management of pterygium.

作者信息

Riordan-Eva P, Kielhorn I, Ficker L A, Steele A D, Kirkness C M

机构信息

Moorfields Eye Hospital, London, UK.

出版信息

Eye (Lond). 1993;7 ( Pt 5):634-8. doi: 10.1038/eye.1993.146.

DOI:10.1038/eye.1993.146
PMID:8287984
Abstract

In a retrospective survey of 117 operations for primary or recurrent pterygium, conjunctival autografting was compared with both excision without conjunctival closure ('bare sclera excision') and excision with complete conjunctival closure. The probability of corneal recurrence at 36 months after surgery was determined by survival curve analysis. In previously unoperated cases conjunctival autografting (n = 15) resulted in a 14% probability of recurrence, compared with 70% for bare sclera excision (n = 50) and 69% for excision with complete conjunctival closure (n = 20). In previously operated cases conjunctival autografting (n = 17) resulted in a 7% probability of recurrence, compared with 82% for bare sclera excision (n = 15). Hazard ratio analysis confirmed the statistical significance of these results at the 95% confidence level. Conjunctival autografting was more likely to produce an improvement in visual acuity than other forms of surgery.

摘要

在一项针对117例原发性或复发性翼状胬肉手术的回顾性调查中,将结膜自体移植术与不进行结膜闭合的切除术(“裸巩膜切除术”)以及完全结膜闭合的切除术进行了比较。通过生存曲线分析确定术后36个月角膜复发的概率。在既往未手术的病例中,结膜自体移植术(n = 15)导致复发概率为14%,而裸巩膜切除术(n = 50)为70%,完全结膜闭合切除术(n = 20)为69%。在既往手术的病例中,结膜自体移植术(n = 17)导致复发概率为7%,而裸巩膜切除术(n = 15)为82%。风险比分析证实了这些结果在95%置信水平上具有统计学意义。结膜自体移植术比其他手术方式更有可能提高视力。

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