Gambale W, Croce J, Costa-Manso E, Croce M, Sales M
Department of Microbiology, University of São Paulo (ICB-USP), Brazil.
J Investig Allergol Clin Immunol. 1993 Jan-Feb;3(1):45-50.
In this study, we investigated the fungi most frequently found in the air and the books of 28 libraries at the University of São Paulo, Brazil. In a second phase, 314 librarians were questioned about the presence of asthmatic or rhinitic symptoms, and the relationship with the site of work. Forty-nine percent of them reported this type of symptoms and 80% related them to the place of work. In the third stage, librarians underwent intracutaneous tests against the 20 fungi most frequently isolated in libraries. Eighteen librarians presented positive tests, 12 of whom reported rhinitis and 6 of whom were asymptomatic. In 19.5% of symptomatic patients wheals > 15 mm were observed after 6 h, while 9% of the asymptomatic patients presented similar wheals. Fourteen librarians with positive tests underwent tests with each of the 20 fungi constituting the pool. The airborne fungi isolated in libraries are likely to be found anywhere in the city of São Paulo, but they are likely to be present in higher concentrations in libraries, subsequently producing respiratory allergies.
在本研究中，我们调查了巴西圣保罗大学28个图书馆空气中和书籍上最常发现的真菌。在第二阶段，对314名图书馆员询问了哮喘或鼻炎症状的出现情况以及与工作场所的关系。其中49%报告有此类症状，80%将其与工作场所相关联。在第三阶段，图书馆员针对图书馆中最常分离出的20种真菌进行了皮内试验。18名图书馆员试验呈阳性，其中12人报告有鼻炎，6人无症状。在19.5%的有症状患者中，6小时后观察到风团大于15毫米，而9%的无症状患者出现类似风团。14名试验呈阳性的图书馆员针对构成样本库的20种真菌中的每一种进行了测试。图书馆中分离出的空气传播真菌可能在圣保罗市的任何地方被发现，但它们在图书馆中的浓度可能更高，随后会引发呼吸道过敏。
