Mohovic J, Gambale W, Croce J
Departamento de Microbiologia, Universidade de São Paulo, Brazil.
Allergol Immunopathol (Madr). 1988 Nov-Dec;16(6):397-402.
With the purpose of measuring the frequency of allergies of the respiratory tract to airborne fungi in São Paulo, Brazil, 201 patients with bronchial asthma and/or allergic rhinitis were submitted to intradermal testings with allergenic extracts of 42 fungus genera isolated from the air in São Paulo. The extracts of these fungi were prepared according to Coca's method and then standardized by the weight by the volume method. At first, the patients were submitted to intradermal testing with the total polyvalent (TP) extract, getting positive reaction in 70 of them (34.8%). The patients with positive reaction to the TP were tested with the 42 individual extracts and 74.3% of them reacted positively to one or more extracts. These results led us to the conclusion that the most frequent fungi in the air of São Paulo were not the ones which cause the highest number of positive intradermal reactions. Therefore, the convenience in employing as many allergens as possible in intradermal testings for diagnosis should be reinforced.
为了测定巴西圣保罗呼吸道对空气传播真菌的过敏频率，201名患有支气管哮喘和/或过敏性鼻炎的患者接受了用从圣保罗空气中分离出的42个真菌属的变应原提取物进行的皮内试验。这些真菌的提取物按照科卡氏方法制备，然后通过重量体积法进行标准化。首先，患者接受了用总多价（TP）提取物进行的皮内试验，其中70人（34.8%）出现阳性反应。对TP呈阳性反应的患者用42种单独的提取物进行测试，其中74.3%的人对一种或多种提取物呈阳性反应。这些结果使我们得出结论，圣保罗空气中最常见的真菌并非引起皮内反应阳性数量最多的真菌。因此，应加强在皮内试验诊断中尽可能使用多种变应原的便利性。
