母乳喂养与儿童癌症。

Breastfeeding and childhood cancer.

作者信息

Mathur G P, Gupta N, Mathur S, Gupta V, Pradhan S, Dwivedi J N, Tripathi B N, Kushwaha K P, Sathy N, Modi U J

机构信息

Department of Pediatrics, Medical College, Kanpur.

出版信息

Indian Pediatr. 1993 May;30(5):651-7.

PMID:8282392

Abstract

Total duration of breastfeeding and of exclusive breastfeeding was studied and compared in 99 childhood cancer cases and 90 controls. The difference between the average duration of breastfeeding in cases and controls was significant (p < 0.05), but when average duration of exclusive breastfeeding was compared in cases and controls the difference was highly significant (p < 0.001). In lymphoma cases and controls the difference between the average duration of breastfeeding was moderately significant (p < 0.01). However, when average duration of exclusive breastfeeding was compared in lymphoma cases and controls the difference was highly significant (p < 0.001). When other cancer groups and controls were compared with respect to their total duration of breastfeeding and duration of exclusive breastfeeding the differences when insignificant (p > 0.05). Cases and controls were not different with respect to their age, sex, birth year, birth order, age and educational status of mothers, smoking of fathers and socioeconomic status. However, a positive family history of cancer was obtained in 4 (4%) of cases whereas in controls it was obtained in only 1 (1.1%).

摘要

对99例儿童癌症病例和90例对照者的母乳喂养总时长及纯母乳喂养时长进行了研究和比较。病例组和对照组母乳喂养的平均时长差异显著（p < 0.05），但比较病例组和对照组的纯母乳喂养平均时长时，差异极为显著（p < 0.001）。在淋巴瘤病例组和对照组中，母乳喂养的平均时长差异中度显著（p < 0.01）。然而，比较淋巴瘤病例组和对照组的纯母乳喂养平均时长时，差异极为显著（p < 0.001）。当比较其他癌症组和对照组的母乳喂养总时长及纯母乳喂养时长时，差异不显著（p > 0.05）。病例组和对照组在年龄、性别、出生年份、出生顺序、母亲的年龄和教育程度、父亲的吸烟情况以及社会经济地位方面无差异。然而，4例（4%）病例有癌症家族史阳性，而对照组仅有1例（1.1%）有癌症家族史阳性。