Mortazavi Hamed, Tashvighi Maryam, Azizian Morteza, Khalighi Hamid Reza, Sabour Siamak, Movahhedian Amir, Baharvand Maryam
Associate Professor, Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences , Tehran, Iran .
Assistant Professor, Department of Hematology and Oncology, Medical School. Azad University , Qom, Iran .
J Clin Diagn Res. 2015 Sep;9(9):ZC80-3. doi: 10.7860/JCDR/2015/11976.6521. Epub 2015 Sep 1.
Cancer is a major cause of death in children under 15 years of age.
This study aimed to evaluate relationship between demographics and dental status in a defined group of Iranian paediatric patients undergoing cancer therapy.
This cross-sectional study was accomplished on 161 subjects age ranging 8-12 years. There were 76 cancerous patients hospitalized at Mahak Hospital (one of the major children's cancer centers in Tehran) as the study group and 85 healthy children attending at Dental School, International Branch of Shahid Beheshti University of Medical Sciences, Tehran, Iran from 2012 to 2013.
Demographics were gathered by using data-form. Oral examination and DMFT Index were used to describe teeth status in all teeth and in the first permanent molars. According to Becker's definition, "D" stands for untreated decayed teeth, "M" indicates missing teeth, and "F" shows Filled teeth. It is noteworthy that full coverage crowns are considered as "F" in this Index.
Chi-square, Mann-Whitney U, Student's t-tests and Logistic Regression were used for data analysis.
The most frequent type of cancer was acute lymphoblastic/lymphocytic leukemia (33.3%). Patients were significantly shorter than controls (p=0.03), and their fathers and mothers were of lower educational achievement (p=0.01, p= 0.001). Although DMFT of all dentition showed significantly higher score in cancerous children (p=0.001), DMFT of four first permanent molars (left, right, upper, and lower) was borderline significantly higher in patients (p= 0.06). Moreover, frequency of cancer was borderline significantly higher in children with lower birth order (p= 0.05). According to Logistic Regression, in as much as patients grew elder 1 year, DMFT index increased 1.5 units.
Patients under cancer therapy were shorter than healthy ones, and their parents were of lower educational levels. In addition, their teeth status was poorer than controls.
癌症是15岁以下儿童的主要死因。
本研究旨在评估接受癌症治疗的特定伊朗儿科患者群体的人口统计学特征与牙齿状况之间的关系。
本横断面研究针对161名年龄在8至12岁的受试者开展。研究组为76名在马哈克医院（德黑兰主要的儿童癌症中心之一）住院的癌症患者，对照组为2012年至2013年在伊朗德黑兰沙希德·贝赫什提医科大学国际分校牙科学院就诊的85名健康儿童。
通过数据表格收集人口统计学信息。采用口腔检查和DMFT指数描述所有牙齿及第一恒磨牙的牙齿状况。根据贝克尔的定义，“D”代表未治疗的龋齿，“M”表示缺失牙，“F”表示填充牙。值得注意的是，在此指数中全冠修复被视为“F”。
采用卡方检验、曼-惠特尼U检验、学生t检验和逻辑回归进行数据分析。
最常见的癌症类型是急性淋巴细胞白血病（33.3%）。患者明显比对照组矮（p = 0.03），其父母的教育程度较低（p = 0.01，p = 0.001）。尽管所有牙列的DMFT在癌症儿童中得分显著更高（p = 0.001），但患者四颗第一恒磨牙（左、右、上、下）的DMFT略高于临界值（p = 0.06）。此外，低出生顺序儿童的癌症发病率略高于临界值（p = 0.05）。根据逻辑回归分析，患者每长大1岁，DMFT指数增加1.5个单位。
接受癌症治疗的患者比健康患者矮，其父母的教育水平较低。此外，他们的牙齿状况比对照组差。
