Ferrini M T, Waitzberg D L, Pasternak J, Coppini L Z, da Silva M de L, Gama-Rodrigues J
Grupo de Apoio Nutricional Enteral e Parenteral, Hospital Beneficência Portuguesa de São Paulo.
Rev Hosp Clin Fac Med Sao Paulo. 1993 Jul-Aug;48(4):161-6.
Fifty-two patients with AIDS-IV C (opportunistic infections) received nutritional supplementation, (enteral diets or total parenteral nutrition) in 60 admission episodes. Most patients had lost more than 10% of their ideal weight; albumin serum level was inferior or equal to 3.0 g/dl at admission in 33.3% of cases, and low serum albumin had a positive correlation with mortality (p less than 0.05%). Lean body mass, indirectly evaluated by 24 hour urinary creatinine excretion was less than 30% of the ideal in 44.7% of cases, and had a positive correlation with death rate. Enteral nutrition was given in 16.7% of episodes, total parenteral nutrition in 35% and in the remaining episodes the patient received only oral supplements. Patients that received TPN spent more time in hospital than patients with enteral nutrition (23.1 more or less 21.3 days against 7.2 more or less 4.8 days). Patients with AIDS IV C are usually undernourished, have low serum albumin and important deficit of lean body mass. Weight loss and low lean body mass are associated positively with mortality. Nutritional support had no influence on mortality rate.
52例艾滋病IV期C型（机会性感染）患者在60次住院期间接受了营养补充（肠内营养或全胃肠外营养）。大多数患者体重减轻超过理想体重的10%；33.3%的患者入院时血清白蛋白水平低于或等于3.0g/dl，低血清白蛋白与死亡率呈正相关（p<0.05%）。通过24小时尿肌酐排泄间接评估的去脂体重，44.7%的患者低于理想值的30%，且与死亡率呈正相关。16.7%的住院期间给予肠内营养，35%给予全胃肠外营养，其余住院期间患者仅接受口服补充剂。接受全胃肠外营养的患者住院时间比接受肠内营养的患者长（分别为23.1±21.3天和7.2±4.8天）。艾滋病IV期C型患者通常营养不良，血清白蛋白水平低，去脂体重严重不足。体重减轻和低去脂体重与死亡率呈正相关。营养支持对死亡率无影响。
