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[复发性渗出性心包炎——秋水仙碱的非传统治疗]

[Recurrent exudative pericarditis--non-traditional therapy with colchicine].

作者信息

Puchala M

机构信息

Kardiologická ambulancia, Nemocnica s poliklinikou Poprad.

出版信息

Vnitr Lek. 1993 Nov;39(11):1052-6.

PMID:8284902
Abstract

Relapses are one of the most serious complications of exudative pericarditis. Optimal treatment which prevents exacerbation of the disease does not exist so far. Non-steroid antiphlogistic drugs are usually drugs of choice. Corticoids are used in more severe conditions or during frequent relapses. Development of a relapse, despite corticoid treatment, calls for more intense and prolonged corticoid treatment even when this treatment produces undesirable side-effects. Surgical methods do not always produce a lasting favourable effect, as the authors observed repeatedly in two patients from the group of patients referred to. The initial therapeutic findings after colchicine treatment in relapsing pericarditis are optimistic but it will be necessary to find in larger groups of patients the optimal method of implementation of this treatment.

摘要

复发是渗出性心包炎最严重的并发症之一。目前尚无能预防疾病加重的最佳治疗方法。非甾体抗炎药通常是首选药物。皮质类固醇用于病情更严重或频繁复发的情况。尽管使用了皮质类固醇治疗,但仍出现复发时,即使这种治疗产生不良副作用,也需要更强化和更长时间的皮质类固醇治疗。手术方法并不总是能产生持久的良好效果,正如作者在所述患者组中的两名患者身上反复观察到的那样。秋水仙碱治疗复发性心包炎的初步治疗结果令人乐观,但有必要在更大规模的患者群体中找到实施这种治疗的最佳方法。

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