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太白贝母化学成分的研究

[Studies on the chemical constituents of Fritillaria taipaiensis L].

作者信息

Hu C H, Shang E N, Lin W H, Cai M S

机构信息

Department of Chemistry, Ningxia Medical College, Yinchuan.

出版信息

Yao Xue Xue Bao. 1993;28(7):516-21.

PMID:8285053
Abstract

A new C-nor-D-homo-steroidal alkaloid named taipaienine, together with five known alkaloids namely chuanbeinone, imperialine, verticinone, perimissine and isoverticine were isolated from the bulbs of Fritillaria taipaiensis L. var. ningxiaensis Y. et W.. The unusual structure of taipaienine was a first sample with a hydroxyl group substituted at C-25 of (22)R-trans quinolizidine moiety with orientation of nitrogen lone pair. Their structures were determined by various spectral analyses.

摘要

从宁夏太白贝母(Fritillaria taipaiensis L. var. ningxiaensis Y. et W.)的鳞茎中分离出一种新的C-去甲-D-高甾体生物碱太白贝母碱,以及五种已知生物碱,即川贝酮、西贝母碱、贝母辛、浙贝母碱甲和异贝母辛。太白贝母碱的独特结构是(22)R-反式喹诺里西啶部分C-25位带有羟基且氮孤对有特定取向的首个样品。通过各种光谱分析确定了它们的结构。

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