Calvo Rey C, Borque Andrés C, del Castillo Martín F, García Piñeiro A, García Hortelano J, García García M, Rubio Vidal D, Moreno Granados F
Servicio de Enfermedades Infecciosas, Hospital Infantil La Paz, Madid.
An Esp Pediatr. 1993 Nov;39(5):423-7.
Between January 1978 and December 1991, 38 patients who fulfilled the CDC (Center for Disease Control) criteria for Kawasaki syndrome were admitted to our hospital. We reviewed the clinical data, laboratory tests, ECG and serial echocardiographic studies in order to establish the characteristics of the disease in our environment. There were 23 males and 15 females. The age at presentation ranged from 4 months to 10 years (mean 3.5 years). Extracardiac complications were as follows: arthritis in 12 patients, vesicular hydrops in 2, urinary tract infection in 1 and lymphocytic meningitis in 1. Cardiac involvement was frequent, with 35% of the patients being diagnosed with coronary pathologies (dilatation of coronary arteries in 9 and aneurysm formations in 4). The most usual location of these anomalies was in the left main coronary artery. By the end to the follow-up period, 71% of the lesions had disappeared. The time necessary for this regression was related to the size of the abnormalities. The high incidence of cardiac involvement make it necessary to follow these patients for a period of time in order to prevent or to treat the later occurring sequelae.
1978年1月至1991年12月期间，38例符合美国疾病控制中心（CDC）川崎综合征标准的患者入住我院。我们回顾了临床资料、实验室检查、心电图及系列超声心动图研究，以确定该病在我们所处环境中的特征。其中男性23例，女性15例。发病年龄为4个月至10岁（平均3.5岁）。心外并发症如下：12例有关节炎，2例有囊状积液，1例有尿路感染，1例有淋巴细胞性脑膜炎。心脏受累很常见，35%的患者被诊断有冠状动脉病变（9例冠状动脉扩张，4例动脉瘤形成）。这些异常最常见的部位是左冠状动脉主干。到随访期末，71%的病变已消失。病变消退所需时间与异常大小有关。心脏受累的高发生率使得有必要对这些患者随访一段时间，以预防或治疗后期出现的后遗症。
