单独以及在过氧化物存在的情况下，铜离子或铁离子对病毒的灭活作用。
Virus inactivation by copper or iron ions alone and in the presence of peroxide.
作者信息
Sagripanti J L, Routson L B, Lytle C D
机构信息
Division of Life Sciences, Food and Drug Administration, Rockville, Maryland 20852.
出版信息
Appl Environ Microbiol. 1993 Dec;59(12):4374-6. doi: 10.1128/aem.59.12.4374-4376.1993.
Abstract
Cupric and ferric ions were able to inactivate five enveloped or nonenveloped, single- or double-stranded DNA or RNA viruses. The virucidal effect of these metals was enhanced by the addition of peroxide, particularly for copper(II). Under the conditions of our test, mixtures of copper(II) ions and peroxide were more efficient than glutaraldehyde in inactivating phi X174, T7, phi 6, Junin, and herpes simplex viruses. The substances described here should be able to inactivate most, if not all, viruses that have been found contaminating medical devices.
摘要
铜离子和铁离子能够使五种包膜或无包膜、单链或双链的DNA或RNA病毒失活。过氧化物的添加增强了这些金属的杀病毒效果，尤其是对于铜离子（II）。在我们的测试条件下，铜离子（II）和过氧化物的混合物在使φX174、T7、φ6、胡宁病毒和单纯疱疹病毒失活方面比戊二醛更有效。这里描述的物质应该能够使大多数（如果不是全部）已发现污染医疗器械的病毒失活。
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