• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

下丘脑性肥胖猴子的体重减轻与血清胰岛素水平

Weight reduction and serum insulin levels in hypothalamic obese monkeys.

作者信息

Hamilton C L, Rabinowitz J L

出版信息

J Med Primatol. 1976;5(5):276-83. doi: 10.1159/000459972.

DOI:10.1159/000459972
PMID:828670
Abstract

Two hyperinsulinemic rhesus monkeys, made obsese (body weight 22 kg) by the placement of hypothalamic lesions, were place on a weight reduction diet for a period of approximately eight months. After losing approximately losing approximately 25% body weight, the animals exhibited a fall in serum insulin levels without changes in plasma glucose levels or composition of fat pad tissue. There was evidence that the number of adipocytes remained constant but were reduced in size after the body weight loss.

摘要

两只患有高胰岛素血症的恒河猴,通过下丘脑损伤致胖(体重22千克),被给予减重饮食约八个月。在体重减轻约25%后,动物血清胰岛素水平下降,而血浆葡萄糖水平或脂肪垫组织成分未发生变化。有证据表明,脂肪细胞数量保持不变,但体重减轻后其大小减小。

相似文献

1
Weight reduction and serum insulin levels in hypothalamic obese monkeys.下丘脑性肥胖猴子的体重减轻与血清胰岛素水平
J Med Primatol. 1976;5(5):276-83. doi: 10.1159/000459972.
2
Adiposity, anthropometric measures, and plasma insulin levels of rhesus monkeys.恒河猴的肥胖、人体测量指标及血浆胰岛素水平
Int J Obes. 1985;9(3):213-24.
3
Obesity in male and female rhesus monkeys: fat distribution, glucoregulation, and serum androgen levels.雄性和雌性恒河猴的肥胖:脂肪分布、葡萄糖调节及血清雄激素水平
J Clin Endocrinol Metab. 1989 Aug;69(2):287-93. doi: 10.1210/jcem-69-2-287.
4
Primary prevention of diabetes mellitus by prevention of obesity in monkeys.通过预防猴子肥胖来进行糖尿病的一级预防。
Diabetes. 1993 Dec;42(12):1809-14. doi: 10.2337/diab.42.12.1809.
5
Assessment of obesity in pigtailed monkeys (Macaca nemestrina).豚尾猴(食蟹猕猴)肥胖情况的评估。
J Med Primatol. 1977;6(3):151-62. doi: 10.1159/000459737.
6
Feeding behavior in monkeys with spontaneous diabetes mellitus.自发性糖尿病猕猴的摄食行为
J Med Primatol. 1975;4(3):145-53. doi: 10.1159/000459848.
7
The course of development of glucose intolerance in the monkey (Macaca mulatta).猕猴(恒河猴)葡萄糖耐量异常的发展过程。
J Med Primatol. 1978;7(3):165-73. doi: 10.1159/000459806.
8
Changes in insulin responses and binding in adipocytes from monkeys with obesity progressing to diabetes.肥胖进展为糖尿病的猴子脂肪细胞中胰岛素反应和结合的变化。
Int J Obes. 1988;12(5):433-43.
9
Elevated plasma cell membrane glycoprotein levels and diminished insulin receptor autophosphorylation in obese, insulin-resistant rhesus monkeys.肥胖、胰岛素抵抗的恒河猴血浆细胞膜糖蛋白水平升高及胰岛素受体自身磷酸化减少。
Metabolism. 2002 Apr;51(4):465-70. doi: 10.1053/meta.2002.31327.
10
Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys.在恒河猴发展为2型糖尿病的过程中,脂肪细胞蛋白脂联素的循环浓度与胰岛素敏感性降低同时下降。
Diabetes. 2001 May;50(5):1126-33. doi: 10.2337/diabetes.50.5.1126.