Brown N P, Harris M L, Shun-Shin G A, Vrensen G F, Willekens B, Bron A J
Clinical Cataract Research Unit, Nuffield Laboratory of Ophthalmology, Oxford, UK.
Eye (Lond). 1993;7 ( Pt 5):672-9. doi: 10.1038/eye.1993.154.
Fibre folds, previously called lamellar separation of the lens, have been found by electron microscopy to be associated with fibre breaks, which are seen in vivo as the circular shades of Obazawa. This led to the present study to determine the relationship between fibre folds, fibre breaks, waterclefts and spoke cataract. All lenses with fibre folds were found to have circular shades. A few instances of circular shades without fibre folds were found, suggesting that the fibre break may be the primary pathology. It was found that circular shades occurred in association with spoke cataract only when fibre folds were also present. Thus there is no essential causal relationship between fibre breaks and spoke cataract. The occurrence of waterclefts was unrelated to the presence of the other features. The lower nasal quadrant of the lens was the most common site for the four features. The depth of spoke cataracts was found to be unrelated to the age of the patient, which makes it unlikely that accommodational stress at the time of onset of presbyopia is causative.
纤维折叠，以前称为晶状体板层分离，通过电子显微镜发现与纤维断裂有关，纤维断裂在体内表现为小泽氏环状阴影。这引发了本研究，以确定纤维折叠、纤维断裂、水裂和辐轮状白内障之间的关系。所有有纤维折叠的晶状体都发现有环状阴影。发现了一些没有纤维折叠的环状阴影实例，这表明纤维断裂可能是主要病理改变。研究发现，只有当纤维折叠也存在时，环状阴影才会与辐轮状白内障同时出现。因此，纤维断裂与辐轮状白内障之间不存在本质的因果关系。水裂的出现与其他特征的存在无关。晶状体的鼻下象限是这四种特征最常见的部位。发现辐轮状白内障的深度与患者年龄无关，这使得老花眼发病时的调节压力不太可能是致病原因。
