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[子宫内膜异位症和子宫腺肌病中雌激素和孕激素受体的研究]

[Study on estrogen and progesterone receptors in endometriosis and adenomyosis].

作者信息

Peng Z, Liu S, He B, Xi M, Cao Z

出版信息

Hua Xi Yi Ke Da Xue Xue Bao. 1993 Sep;24(3):290-2.

PMID:8288201
Abstract

Estrogen and progesterone receptors (ER and PR) in 18 cases of ovarian endometriosis and 13 cases of adenomyosis were determined with dextran coated charcoal (DCC) method. The levels of ER and PR in those specimens were lower than those of normal endometrium. Among the 18 cases of ovarian endometriosis, 6 (33.4%) were negative for PR, which accounted for the unsatisfactory results of progesterone treatment for some endometriosis. In the 13 cases of adenomyosis there were 10 (76.9%) showing positive PR. It is suggested that the hormone therapy may be useful to treat those young patients with adenomyosis instead of surgery. The correlation of the ER and PR levels, the treatment and prognosis in endometriosis and adenomyosis are worth further studying.

摘要

采用葡聚糖包被活性炭(DCC)法检测18例卵巢子宫内膜异位症和13例子宫腺肌病患者的雌激素和孕激素受体(ER和PR)。这些标本中ER和PR的水平低于正常子宫内膜。在18例卵巢子宫内膜异位症患者中,6例(33.4%)PR为阴性,这是一些子宫内膜异位症患者孕激素治疗效果不佳的原因。在13例子宫腺肌病患者中,10例(76.9%)PR呈阳性。提示激素治疗可能对那些年轻的子宫腺肌病患者有用,而非手术治疗。子宫内膜异位症和子宫腺肌病中ER和PR水平、治疗及预后的相关性值得进一步研究。

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