Fischl M A
Comprehensive AIDS Program, University of Miami School of Medicine.
Hosp Pract (Off Ed). 1994 Jan 15;29(1):43-8. doi: 10.1080/21548331.1994.11442959.
Despite recent disappointment with antiretroviral agents, investigators continue to examine combination therapy with agents that target the same or different stages of the HIV life cycle. Initial studies suggest that when therapy is started early in the course of infection, certain combinations may be better than single-drug regimens in reducing viral burden and delaying the onset of drug resistance.
尽管近期抗逆转录病毒药物令人失望,但研究人员仍在继续研究使用针对人类免疫缺陷病毒(HIV)生命周期相同或不同阶段的药物进行联合治疗。初步研究表明,在感染过程早期开始治疗时,某些联合治疗方案在降低病毒载量和延缓耐药性出现方面可能比单一药物治疗方案更好。