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8例自发性食管破裂的临床研究

[Clinical study of 8 cases of spontaneous esophageal rupture].

作者信息

Okitsu H, Takagi Y, Satou S, Kimura K, Uyama T, Monden Y

机构信息

Second Department of Surgery, Tokushima University School of Medicine, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1993 Dec;41(12):2409-13.

PMID:8288934
Abstract

Among 8 patients with spontaneous esophageal rupture, mean age was 46.5 years, and there was only one female. Vomiting after drinking was the main cause of onset. In 4 patients who underwent drainage of the thoracic cavity or initial treatment by surgery within 24 hrs after onset, closure after layer-layer suture of the site of rupture was made in two patients in whom definitive diagnosis was obtained at the first medical examination and early discharge was possible. A definitive diagnosis was obtained after drainage of the thoracic cavity in the other two patients, and esophagectomy without thoracotomy was performed on the 55th day after onset in one and the other patient received only conservative treatment without surgery, both patients were discharged. Of 4 patients who underwent treatment after 24 hrs, two patients who recovered included one who received only conservative treatment and another who underwent closure by suture of the site of rupture and covering with a pedicled omental flap 12 days after onset. The other two patients died of MOF after operation. We propose the following guidelines for treatment of this condition; In patients in whom surgical treatment is possible within 24 hrs after onset, closure by layer-layer suture of the site of rupture may be indicated. In cases in which more than 24 hrs has elapsed after rupture spontaneous closure sometimes can be expected in patients with a rupture would less than 2 cm. In patients accompanied with progressing mediastinitis or pyothorax with drainage procedure surgical treatment is indicated.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在8例自发性食管破裂患者中,平均年龄为46.5岁,仅有1名女性。酒后呕吐是主要发病原因。4例在发病后24小时内接受胸腔引流或手术初始治疗的患者中,2例在首次医学检查时获得明确诊断且可早期出院,对破裂部位进行分层缝合后闭合。另外2例患者在胸腔引流后获得明确诊断,其中1例在发病后第55天行非开胸食管切除术,另1例仅接受保守治疗未手术,两例患者均出院。4例在24小时后接受治疗的患者中,2例康复,1例仅接受保守治疗,另1例在发病后12天对破裂部位进行缝合并带蒂大网膜瓣覆盖后闭合。另外2例患者术后死于多器官功能衰竭。我们提出以下本病的治疗指南:发病后24小时内可进行手术治疗的患者,可考虑对破裂部位进行分层缝合闭合。破裂后超过24小时,破裂口小于2 cm的患者有时可期待自发闭合。伴有进行性纵隔炎或脓胸且需引流的患者,应进行手术治疗。(摘要截短至250字)

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