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[实验性和自发性感染期间猪体内鸟分枝杆菌和胞内分枝杆菌的毒力]

[Virulence of Mycobacterium avium and Mycobacterium intracellulare in pigs during experimental and spontaneous infection].

作者信息

Pavlas M, Patloková V

出版信息

Vet Med (Praha). 1976 Nov;21(11):683-92.

PMID:828995
Abstract

The virulence of M. avium and M. intracellulare was studied in 16 experimentally infected pigs and on 174 animals coming from herds spontaneously infected with the mentioned Mycobacterium species. The result of the patho-anatomic examination and cultivation from samples of lymph nodes, organs, muscles, and excrements proved a higher virulence of M. avium to experimentally and spontaneously infected pigs, as compared with M. intracellulare. The strains of M. avium and M. intracellulare sensibilized all pigs to aviary tuberculin within 80 days from peroral and intranasal infection. Patho-anatomic changes in pigs spontaneously infected with M. avium were proved in 10% of the animals that showed a negative reaction to aviary tuberculin.

摘要

在16头实验感染猪以及174头来自自然感染上述分枝杆菌属菌群猪群的动物身上,研究了鸟分枝杆菌和胞内分枝杆菌的毒力。对淋巴结、器官、肌肉和排泄物样本进行的病理解剖检查及培养结果表明,与胞内分枝杆菌相比,鸟分枝杆菌对实验感染和自然感染猪的毒力更高。从经口和鼻内感染起80天内,鸟分枝杆菌和胞内分枝杆菌菌株使所有猪对禽结核菌素敏感。在对禽结核菌素呈阴性反应的动物中,10%的猪被证实发生了自然感染鸟分枝杆菌的病理解剖变化。

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