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酒精对光肌阵挛和光惊厥反应的影响(作者译)

[Influence of alcohol on photomyoclomus and photoconvulsive response (author's transl)].

作者信息

Klingler D, Wessely P

出版信息

EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1976 Jun;7(2):81-6.

PMID:829052
Abstract

In some subjects with increased light sensitivity to intermittent photic stimulation it could be observed: (1) a photomyoclonic response (PMR)--(in the EEG: muscular and ocular artefacts and probably spikes) including twitching of the facial, and sometimes muscles (Fig. 1 and 2) a photoconvulsive response (PKR), which deals in EEG with paroxismal cerebral potentials (Fig. 2). 20 min after consumation of small doses of alcohol (60 ml brandy) the PMR persists, while the photomyoclunus response gets extinguished (Fig. 3). In special terms there can be a development of epileptic seizures without alcohol (Fig. 4a-b), which fail to appear after alcohol up to 3 hours. This effect is demonstrated in six cases (Tab. 1). A partial anticonvulsive effect of alcohol is possible to be involved, especially in cases of fits with motoric actions (myoclunisms). The cilical valence of PMR and PKR seems to be the same, as a conductive factor to the liability to cerebral fits.

摘要

在一些对间歇性光刺激光敏感性增加的受试者中,可以观察到:(1)光肌阵挛反应(PMR)(脑电图表现为:肌肉和眼部伪迹以及可能的棘波),包括面部抽搐,有时还有肌肉抽搐(图1和图2);(2)光惊厥反应(PKR),脑电图表现为阵发性脑电位(图2)。饮用小剂量酒精(60毫升白兰地)20分钟后,PMR持续存在,而光肌阵挛反应消失(图3)。在特定情况下,无酒精时可能会发生癫痫发作(图4a - b),但饮酒后长达3小时内癫痫发作不会出现。这种效应在6例患者中得到证实(表1)。酒精可能具有部分抗惊厥作用,尤其是在伴有运动动作(肌阵挛)的发作病例中。作为大脑癫痫易感性的传导因素,PMR和PKR的临床效价似乎相同。

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1
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EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1976 Jun;7(2):81-6.
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