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[长波激光辐射对健康人和肺结核患者血液淋巴细胞中烟酰胺腺嘌呤二核苷酸磷酸(NADP)依赖性脱氢酶活性的影响]

[The effect of long-wave laser radiation on the NADP-dependent dehydrogenase activity of the blood lymphocytes in healthy persons and pulmonary tuberculosis patients].

作者信息

Savchenko A A, Borisov A G, Glozman N E

出版信息

Probl Tuberk. 1993(6):35-8.

PMID:8290529
Abstract

A study was made to elucidate the in vitro effects of long-wave laser irradiation on NAD(P)-dependent lymphocytic dehydrogenases in peripheral blood of healthy subjects and patients with fibrous-cavernous tuberculosis of the lungs. In addition to suppression of T-cell immunity and reinforcement of humoral factors, such patients demonstrated predominance of catabolic processes over anabolic, reduction of the substrate flow by Krebs cycle. The above phenomena explain different responses to long-wave laser irradiation (632 nm) in healthy subjects and tuberculous patients who are noticed to develop more active transfer of the lipid catabolism products to glycolysis.

摘要

开展了一项研究,以阐明长波激光照射对健康受试者及肺部纤维空洞型肺结核患者外周血中NAD(P)依赖性淋巴细胞脱氢酶的体外作用。除了T细胞免疫受到抑制和体液因子增强外,这类患者还表现出分解代谢过程超过合成代谢,三羧酸循环的底物流量减少。上述现象解释了健康受试者和肺结核患者对长波激光照射(632纳米)的不同反应,人们注意到肺结核患者脂质分解代谢产物向糖酵解的转移更为活跃。

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