López Pardo F, González Barrero A, Serrano Castro V, Andreu Alvarez J, Navarrete Ortega M, Burgos Cornejo J
Servicio de Cardiología, Hospital Universitario Virgen del Rocío, Sevilla.
Rev Esp Cardiol. 1993 Nov;46(11):758-60.
The cholesterol embolization is a rare complication of atherosclerosis. A direct implication of the treatment with anticoagulants in the etiology of the disease has been questioned, and now such therapy is considered more as an adjuvant factor with angiographic procedures than as a cause. A 60-year-old patient with an ischemic cardiomyopathy presented cholesterol embolization syndrome, confirmed by cutaneous biopsy histologic examination during treatment with heparin. Spontaneous evolution was favourable and only limited amputation of the lower limbs were required. The authors think that cholesterol emboli have a direct relationship to the treatment with heparin in this case, there being no other causes to justify its appearance.
胆固醇栓塞是动脉粥样硬化的一种罕见并发症。抗凝治疗在该疾病病因中的直接作用受到质疑，现在这种治疗更多地被视为血管造影术的辅助因素而非病因。一名60岁的缺血性心肌病患者出现胆固醇栓塞综合征，在肝素治疗期间经皮肤活检组织学检查得以证实。病情自然转归良好，仅需对下肢进行有限截肢。作者认为，在该病例中胆固醇栓子与肝素治疗有直接关系，没有其他原因可解释其出现。
